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Prevalence and risk of residual viremia after ART in low- and middle-income countries: A cross-sectional study.


ABSTRACT:

Abstract

In order to design effective strategies to eradicate the HIV, an understanding of persistent viral reservoirs is needed. Many studies have demonstrated HIV residual viremia prevalence in high income countries, data from low- and middle-income countries (LMIC) are limited. We assessed the prevalence, and factors associated with residual viremia in people with HIV (PWH), who were virally-suppressed on antiretroviral therapy (ART) in LMIC. We also compared residual viremia prevalence between the LMIC and US.This is a cross-sectional, retrospective study that utilized stored specimen samples from the AIDS clinical trials group (ACTG) studies A5175 and A5208. The last available sample among participants with plasma HIV RNA < 400 copies/mL for ≥3 years were tested by the HIV mol

SUBMITTER: Gatechompol S 

PROVIDER: S-EPMC8415996 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature