Lifestyle Score and Genetic Factors With Hypertension and Blood Pressure Among Adults in Rural China.

ABSTRACT: Background: Although high genetic risk and unhealthful lifestyles are associated with a high risk of hypertension, but the combined relationship between lifestyle score and genetic factors on blood pressure remains limited, especially in resource-constrained areas. Aim: To explore the separate and joint effects between genetic and lifestyle factors on blood pressure and hypertension in rural areas. Methods: In 4,592 adults from rural China with a 3-year of follow-up, a genetic risk score (GRS) was established using 13 single nucleotide polymorphisms (SNPs) and the lifestyle score was calculated including factors diet, body mass index (BMI), smoking status, drinking status, and physical activity. The associations of genetic and lifestyle factors with blood pressure and

SUBMITTER: Niu M 

PROVIDER: S-EPMC8416040 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature