A 4-Gene Signature Associated With Recurrence in Low- and Intermediate-Risk Endometrial Cancer.

ABSTRACT:

Background

The molecular profile of endometrial cancer has become an important tool in determining patient prognosis and their optimal adjuvant treatment. In addition to The Cancer Genome Atlas (TCGA), simpler tools have been developed, such as the Proactive Molecular Risk Classifier for Endometrial Cancer (ProMisE). We attempted to determine a genetic signature to build a recurrence risk score in patients diagnosed with low- and intermediate-risk endometrial cancer.

Methods

A case-control study was conducted. The eligible patients were women diagnosed with recurrence low- and intermediate-risk endometrial cancer between January 2009 and December 2014 at a single institution; the recurrence patients were matched to two nonrecurrence patients with the same diagnosis by age an

SUBMITTER: de Andrade DAP 

PROVIDER: S-EPMC8416164 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature