Demystifying Cell Cycle Arrest by HIV-1 Vif.

ABSTRACT: Although APOBEC3 degradation is the canonical function of HIV-1 Vif, this viral protein also induces potent cell cycle arrest through a newly defined mechanism. Here, we review recent advances in this area and propose that the scope of this activity may go beyond subversion of the host cell cycle.

SUBMITTER: Salamango DJ 

PROVIDER: S-EPMC8416294 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature