Parechovirus and enteroviruses among young infants with sepsis in Iran.

ABSTRACT:

Background and objectives

Human parechoviruses (HPeV) and Human enteroviruses (EV) frequently cause a sepsis-like illness in young infants (younger than three months). Therefore, this study was conducted to determine the frequency of HPeV and EV among the young infants with clinical signs and symptoms of sepsis in Ahvaz city, Iran.

Materials and methods

The blood specimens were collected from 100 (younger than 90 days hospitalized infants) including 54 (56.25%) males and 46 (43.75%) females with clinical signs and symptoms of sepsis-like disease. The RNA was extracted and tested for detection of VP1 region of HPeV and 5 UTR (Untranslated Region) of EV by RT-PCR. The sequences of positive of HPeV were further analyzed to determine HPeV genotyping.

Results

5/100 (5%) of

SUBMITTER: Makvandi M 

PROVIDER: S-EPMC8416594 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature