Timing and Clinical Significance of Fluid Overload in Pediatric Acute Respiratory Distress Syndrome.

ABSTRACT:

Objectives

Fluid overload is associated with worse outcomes in adult and pediatric acute respiratory distress syndrome. However, the time-course of fluid overload and its relationship to outcome has not been described. We aimed to determine the relationship between the timing of fluid overload and outcomes over the first 7 days after acute respiratory distress syndrome onset in children.

Design

Retrospective cohort study.

Setting

Single tertiary care PICU.

Patients

Intubated children with acute respiratory distress syndrome between 2011 and 2019.

Interventions

None.

Measurements and main results

Daily and cumulative total fluid intake, total output, urine output, and fluid balance were collected for each 24-hour period from days 1 to 7 after acute

SUBMITTER: Black CG 

PROVIDER: S-EPMC8416695 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature