Skull base repair following endonasal pituitary and skull base tumour resection: a systematic review.

ABSTRACT:

Purpose

Postoperative cerebrospinal fluid rhinorrhoea (CSFR) remains a frequent complication of endonasal approaches to pituitary and skull base tumours. Watertight skull base reconstruction is important in preventing CSFR. We sought to systematically review the current literature of available skull base repair techniques.

Methods

Pubmed and Embase databases were searched for studies (2000-2020) that (a) reported on the endonasal resection of pituitary and skull base tumours, (b) focussed on skull base repair techniques and/or postoperative CSFR risk factors, and (c) included CSFR data. Roles, advantages and disadvantages of each repair method were detailed. Random-effects meta-analyses were performed where possible.

Results

193 studies were included. Repair methods w

SUBMITTER: Khan DZ 

PROVIDER: S-EPMC8416859 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature