Biomechanics of urinary bladder: slow-filling and slow-emptying cystometry and accommodation.

ABSTRACT:

Objective

In a concept of accommodation of detrusor pressure to volume as an autonomous potency of the bladder, a crucial physiological biomechanical role has been attributed to spontaneous contraction activity. This concept is experimentally investigated on pig bladder in vitro.

Methods

Slowly emptying of not-stimulated pig bladders via a flow resistor has been recorded and the effect of spontaneous contractions on the tonic pressure during emptying by expulsion has been studied.

Results

The expulsed volume can be separated in a reduction of elastic volume and of rest volume. Tonic pressure is determined by the elastic volume in combination with elastic compliance. In an accommodated state completely transient superimposed pressure waves affect rest vol

SUBMITTER: van Duyl WA 

PROVIDER: S-EPMC8417037 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature