Association of IL-17A Polymorphism with Chronic Periodontitis in Type 1 Diabetic Patients.

ABSTRACT:

Statement of the problem

The association of genetic polymorphisms with periodontitis has been studied extensively. The interleukin -17 (IL-17) is a group of cytokines, which comprises six different molecules (IL-17A, B, C, D, E & F). Among these, IL-17A & F are the most commonly understood cytokine, which plays a critical role in inflammatory diseases and periodontal inflammation.

Purpose

To evaluate whether IL-17A gene polymorphism is associated with increased risk of chronic periodontitis in type 1 diabetes patients.

Materials and method

This quantitative case- control study was carried out in 60 subjects in 4 groups. The study groups included group A: 15 type 1 diabetes patients (T1DM) with chronic periodontitis (CP), group B: 15 T1DM patients without CP, group C:

SUBMITTER: Pk SK 

PROVIDER: S-EPMC8417545 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature