Estimates of cortical column orientation improve MEG source inversion.

ABSTRACT: Determining the anatomical source of brain activity non-invasively measured from EEG or MEG sensors is challenging. In order to simplify the source localization problem, many techniques introduce the assumption that current sources lie on the cortical surface. Another common assumption is that this current flow is orthogonal to the cortical surface, thereby approximating the orientation of cortical columns. However, it is not clear which cortical surface to use to define the current source locations, and normal vectors computed from a single cortical surface may not be the best approximation to the orientation of cortical columns. We compared three different surface location priors and five different approaches for estimating dipole vector orientation, both in simulations and visual and mo

SUBMITTER: Bonaiuto JJ 

PROVIDER: S-EPMC8417767 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature