Outcomes and Prognostic Factors of Patients with Metastatic Colorectal Cancer Who Underwent Pulmonary Metastasectomy with Curative Intent: A Brazilian Experience.

ABSTRACT:

Background

We aimed to identify clinicopathological and molecular features associated with progression-free survival (PFS) and overall survival (OS) after pulmonary metastasectomy for metastatic colorectal cancer in a retrospective cohort in Brazil.

Materials and methods

We did a retrospective review of thoracic surgeries performed in a single large academic hospital in Brazil from January 1985 to September 2019. Demographics, previously described prognostic factors, and clinicopathological and molecular characteristics were abstracted. Univariate Cox regression was performed for each variable, and, when significant, data were dichotomized to provide clinically meaningful thresholds.

Results

Records from 698 patients were reviewed. Fifty-eight patients underwent pulmo

SUBMITTER: Gossling GCL 

PROVIDER: S-EPMC8417851 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature