Plant-Based Diet Index and Metabolic Risk in Men: Exploring the Role of the Gut Microbiome.

ABSTRACT:

Background

Healthy plant-based diet index (hPDI) is associated with a lower risk of cardiometabolic conditions, but its association as well as interactions with microbiome have not been elucidated.

Objectives

We aimed to investigate the interrelations between hPDI, gut microbiome, and cardiometabolic risk markers.

Methods

hPDI was derived from dietary assessments by a validated FFQ and was examined in relation to metagenomic profiles of 911 fecal samples collected from 303 men aged 71 ± 4 y with an average BMI (in kg/m2) of 25.2 ± 3.6 in the Men's Lifestyle Validation Study. Principal coordinate (PCo) analysis based on Bray-Curtis dissimilarity was conducted, and interactions between hPDI and PCo were examined by using a metabolic risk score composed of blood lipids,

SUBMITTER: Li Y 

PROVIDER: S-EPMC8417919 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature