Single Nucleotide Polymorphisms in CD36 Are Associated with Macular Pigment among Children.

ABSTRACT:

Background

High macular pigment optical density (MPOD) has been associated with improved eye health and better cognitive functions. Genetic variations have been associated with MPOD in adults. However, these associations between genetic variations and MPOD have not been studied in children.

Objectives

This was a secondary analysis of the FK2 (Fitness Improves Thinking in Kids 2) trial (n = 134, 41% male). The aim was to determine differences in MPOD among children (aged 7-9 y) based on genetic variants that either are biologically relevant to lutein (L) and zeaxanthin (Z) accumulation or have been associated with MPOD in adults.

Methods

MPOD was measured using customized heterochromatic flicker photometry via a macular densitometer. DXA was used to assess whole-body a

SUBMITTER: Liu R 

PROVIDER: S-EPMC8417927 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature