The neuroimaging evidence of brain abnormalities in functional movement disorders.

ABSTRACT: Neuroimaging has been pivotal in identifying and reframing our understanding of functional movement disorders. If accessible, it compensates for the limitations of the clinical exam and is especially useful where there is overlap of functional symptoms with classical presentations of disease. Imaging in functional movement disorders has increasingly identified structural and functional abnormalities that implicate hypoactivation of the cortical and subcortical motor pathways and increased modulation by the limbic system. Neurobiological theories suggest an impaired sense of agency, faulty top-down regulation of motor movement and abnormal emotional processing in these individuals. This framework challenges our traditional understanding of functional movement disorders as distinct from the

SUBMITTER: Sasikumar S 

PROVIDER: S-EPMC8418342 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature