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Dataset Information

C-terminal domain phosphatase-like 1 (CPL1) is involved in floral transition in Arabidopsis.


ABSTRACT:

Background

RNA polymerase II plays critical roles in transcription in eukaryotic organisms. C-terminal Domain Phosphatase-like 1 (CPL1) regulates the phosphorylation state of the C-terminal domain of RNA polymerase II subunit B1, which is critical in determining RNA polymerase II activity. CPL1 plays an important role in miRNA biogenesis, plant growth and stress responses. Although cpl1 mutant showes delayed-flowering phenotype, the molecular mechanism behind CPL1's role in floral transition is still unknown.

Results

To study the role of CPL1 during the floral transition, we first tested phenotypes of cpl1-3 mutant, which harbors a point-mutation. The cpl1-3 mutant contains a G-to-A transition in the second exon, which results in an amino acid substitution from Glu to Lys (E

SUBMITTER: Yuan C 

PROVIDER: S-EPMC8418720 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature