Cardiac Outcomes in Isolated Heart and Simultaneous Kidney and Heart Transplants in the United States.

ABSTRACT:

Introduction

Kidney dysfunction is not uncommon in patients with advanced heart failure. Simultaneous kidney and heart transplants (SKHTs) have gained acceptance as a treatment for patients with end-stage heart failure and severe kidney dysfunction. United States saw a rise of 650% in SKHT from 2000 to 2019. Despite increasing number of SKHT, the selection criteria remain poorly defined and vary across transplant centers.

Methods

We evaluated patient and cardiac allograft survival for SKHT and heart transplant alone (HTA) using the United Network for Organ Sharing (UNOS) database. We then performed a subgroup analysis in recipients with post-transplant acute kidney injury requiring renal replacement therapy (RRT) and compared outcomes between SKHT and HTA recipients.

Resu

SUBMITTER: Agarwal KA 

PROVIDER: S-EPMC8418976 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature