Kaposi Sarcoma Incidence, Burden, and Prevalence in United States People with HIV, 2000-2015.

ABSTRACT:

Background

The introduction of combination antiretroviral therapy (cART) has led to a significant reduction in Kaposi sarcoma (KS) incidence among people with HIV (PWH). However, it is unclear if incidence has declined similarly across key demographic and HIV transmission groups and the annual number of incident and prevalent KS cases remains unquantified.

Methods

Using population-based registry linkage data, we evaluated temporal trends in KS incidence using adjusted Poisson regression. Incidence and prevalence estimates were applied to CDC HIV surveillance data, to obtain the number of incident (2008-2015) and prevalent (2015) cases in the United States.

Results

Among PWH, KS rates were elevated 521-fold [95% confidence intervals (CI), 498-536] compared with the gen

SUBMITTER: Peprah S 

PROVIDER: S-EPMC8419027 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature