3D Atlas of the Pituitary Gland of the Model Fish Medaka (Oryzias latipes).

ABSTRACT: In vertebrates, the anterior pituitary plays a crucial role in regulating several essential physiological processes via the secretion of at least seven peptide hormones by different endocrine cell types. Comparative and comprehensive knowledge of the spatial distribution of those endocrine cell types is required to better understand their physiological functions. Using medaka as a model and several combinations of multi-color fluorescence in situ hybridization, we present the first 3D atlas revealing the gland-wide distribution of seven endocrine cell populations: lactotropes, thyrotropes, Lh and Fsh gonadotropes, somatotropes, and pomca-expressing cells (corticotropes and melanotropes) in the anterior pituitary of a teleost fish. By combining in situ hybridizat

SUBMITTER: Royan MR 

PROVIDER: S-EPMC8419251 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature