Identification and Characteristics of Fusion Peptides Derived From Enveloped Viruses.

ABSTRACT: Membrane fusion events allow enveloped viruses to enter and infect cells. The study of these processes has led to the identification of a number of proteins that mediate this process. These proteins are classified according to their structure, which vary according to the viral genealogy. To date, three classes of fusion proteins have been defined, but current evidence points to the existence of additional classes. Despite their structural differences, viral fusion processes follow a common mechanism through which they exert their actions. Additional studies of the viral fusion proteins have demonstrated the key role of specific proteinogenic subsequences within these proteins, termed fusion peptides. Such peptides are able to interact and insert into membranes for which they hold interest

SUBMITTER: Lozada C 

PROVIDER: S-EPMC8419435 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature