Brain and heart-specific death in cancer patients: Population-based study.

ABSTRACT:

Background

The occurrence of cardiovascular events is a major cause of death in patients with cancer. Small studies have documented a connection between specific brain alterations and autonomic cardiac dysfunctions, possibly resulting in a worse prognosis. We aimed to refine the knowledge of fatal cardiac events in patients with brain metastasis (BM).

Methods

We performed a Surveillance, Epidemiology, and End Results SEER registry-based investigation (timeline: 2010-2016) and extracted all the advanced patients who had experienced fatal cardiac outcomes. Populations were compared according to the presence or not BM. Kaplan-Meier (KM) methodology was used for survival analysis and a multivariate model was developed by adjusting for multiple possible confounders.

Results

SUBMITTER: Safi M 

PROVIDER: S-EPMC8419745 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature