Combining malaria vaccination with chemoprevention: a promising new approach to malaria control.

ABSTRACT: Malaria control has stalled in a number of African countries and novel approaches to malaria control are needed for these areas. The encouraging results of a recent trial conducted in young children in Burkina Faso and Mali in which a combination of the RTS,S/AS01_E malaria vaccine and seasonal malaria chemoprevention led to a substantial reduction in clinical cases of malaria, severe malaria, and malaria deaths compared with the administration of either intervention given alone suggests that there may be other epidemiological/clinical situations in which a combination of malaria vaccination and chemoprevention could be beneficial. Some of these potential opportunities are considered in this paper. These include combining vaccination with intermittent preventive treatment of mala

SUBMITTER: Greenwood B 

PROVIDER: S-EPMC8419817 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature