Evaluation of Xpert GBS assay and Xpert GBS LB assay for detection of Streptococcus agalactiae.

ABSTRACT:

Background

Group B Streptococcal (GBS) infection is the primary agent of neonatal morbidity and mortality. Rapid and simple methods to detect GBS are Xpert GBS and GBS LB assays based on real-time polymerase chain reaction (PCR). However, since the diagnostic accuracy of the two techniques in diagnosing GBS remains unclear, we designed this study to appraise the diagnostic accuracy of the aforementioned.

Methods

A systematic search of all literature published before July 16, 2020 was conducted using Embase, PubMed, Web of Science, and Cochrane Library. The study quality was evaluated through Review Manager 5.3. Accordingly, data extracted in the included studies were analyzed using Meta-DiSc 1.4 and Stata 12.0 software. The diagnosis odds ratio (DOR) and bivariate boxplot we

SUBMITTER: Han MY 

PROVIDER: S-EPMC8419907 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature