Dynamic transcriptome profiles of postnatal porcine skeletal muscle growth and development.

ABSTRACT:

Background

Skeletal muscle growth and development are closely associated with the quantity and quality of pork production. We performed a transcriptomic analysis of 12 Longissimus dorsi muscle samples from Tibetan piglets at four postnatal stages of 0, 14, 30, and 60 days using RNA sequencing.

Results

According to the pairwise comparisons between the libraries of the muscle samples at the four postnatal stages, a total of 4115 differentially expressed genes (DEGs) were identified in terms of |log₂(fold change)| ≥ 1 and an adjusted P value < 0.01. Short-time series expression miner (STEM) analysis of the DEGs identified eight significantly different expression profiles, which were divided into two clusters based on the expression pattern. DEGs in cluster I displaye

SUBMITTER: Wang Y 

PROVIDER: S-EPMC8419915 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature