Triglyceride glucose-body mass index and the risk of diabetes: a general population-based cohort study.

ABSTRACT:

Background

Triglyceride glucose-body mass index (TyG-BMI) has been proven to be a reliable substitute for insulin resistance. However, whether a causal association exists between TyG-BMI and new-onset diabetes remains uncertain. The purpose of this study was to investigate the causal association and predictive performance between TyG-BMI and diabetes.

Methods

A total of 116,661 subjects who underwent a physical examination were included in this study. The subjects were divided into five equal points according to the quintile of TyG-BMI, and the outcome of interest was the occurrence of diabetic events. TyG-BMI = ln [fasting plasma glucose (mg/dL) × fasting triglycerides (mg/dL)/2] × BMI.

Results

During the average follow-up period of 3.1 (0.95) years, 1888 men (1.61 %

SUBMITTER: Wang X 

PROVIDER: S-EPMC8420033 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature