The full spectrum of ethical issues in pediatric genome-wide sequencing: a systematic qualitative review.

ABSTRACT:

Background

The use of genome-wide sequencing in pediatric medicine and research is growing exponentially. While this has many potential benefits, the normative and empirical literature has highlighted various ethical issues. There have not been, however, any systematic reviews of these issues. The aim of this systematic review is to determine systematically the spectrum of ethical issues that is raised for stakeholders in in pediatric genome-wide sequencing.

Methods

A systematic review in PubMed and Google Books (publications in English or German between 2004 and 2021) was conducted. Further references were identified via reference screening. Data were analyzed and synthesized using qualitative content analysis. Ethical issues were defined as arising when a relevant normativ

SUBMITTER: Eichinger J 

PROVIDER: S-EPMC8420043 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature