Molecular mimicry between SARS-CoV-2 and the female reproductive system.

ABSTRACT:

Introduction

Oogenesis, the process of egg production by the ovary, involves a complex differentiation program leading to the production of functional oocytes. This process comprises a sequential pathway of steps that are finely regulated. The question related to SARS-CoV-2 infection and fertility has been evoked for several reasons, including the mechanism of molecular mimicry, which may contribute to female infertility by leading to the generation of deleterious autoantibodies, possibly contributing to the onset of an autoimmune disease in infected patients.

Objective

The immunological potential of the peptides shared between SARS-CoV-2 spike glycoprotein and oogenesis-related proteins; Thus we planned a systematic study to improve our understanding of the possible effects

SUBMITTER: Dotan A 

PROVIDER: S-EPMC8420155 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature