A Direct Comparison of Node and Element-Based Finite Element Modeling Approaches to Study Tissue Growth.

ABSTRACT: Finite element analysis is a useful tool to model growth of biological tissues and predict how growth can be impacted by stimuli. Previous work has simulated growth using node-based or element-based approaches, and this implementation choice may influence predicted growth, irrespective of the applied growth model. This study directly compared node-based and element-based approaches to understand the isolated impact of implementation method on growth predictions by simulating growth of a bone rudiment geometry, and determined what conditions produce similar results between the approaches. We used a previously reported node-based approach implemented via thermal expansion and an element-based approach implemented via osmotic swelling, and we derived a mathematical relationship to relate the

SUBMITTER: Howe D 

PROVIDER: S-EPMC8420794 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature