Ontology highlight
ABSTRACT: Background
Drug supply disruptions have increased during the COVID-19 pandemic, especially for medicines used in the ICU. Despite reported shortages in wealthy countries, global analyses of ICU drug purchasing during COVID-19 are limited.Research question
Has COVID-19 impacted global drug purchases of first-, second-, and third-choice agents used in intensive care?Study design and methods
We conducted a cross-sectional time series study in a global pharmacy sales dataset comprising approximately 60% of the world's population. We analyzed pandemic-related changes in units purchased per 1,000 population for 69 ICU agents. Interventional autoregressive integrated moving average models tested for significant changes when the pandemic was declared (March 2020) and during
SUBMITTER: Callaway Kim K
PROVIDER: S-EPMC8421073 | biostudies-literature | 2021 Dec
REPOSITORIES: biostudies-literature