Improved cortical surface reconstruction using sub-millimeter resolution MPRAGE by image denoising.

ABSTRACT: Automatic cerebral cortical surface reconstruction is a useful tool for cortical anatomy quantification, analysis and visualization. Recently, the Human Connectome Project and several studies have shown the advantages of using T₁-weighted magnetic resonance (MR) images with sub-millimeter isotropic spatial resolution instead of the standard 1-mm isotropic resolution for improved accuracy of cortical surface positioning and thickness estimation. Nonetheless, sub-millimeter resolution images are noisy by nature and require averaging multiple repetitions to increase the signal-to-noise ratio for precisely delineating the cortical boundary. The prolonged acquisition time and potential motion artifacts pose significant barriers to the wide adoption of cortical surface reconstruction

SUBMITTER: Tian Q 

PROVIDER: S-EPMC8421085 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature