A mixed-method feasibility study of a novel transitional regime of incremental haemodialysis: study design and protocol.

ABSTRACT:

Background

Incremental haemodialysis/haemodiafiltration (HD) may help reduce early mortality rates in patients starting HD. This mixed-method feasibility study aims to test the acceptability, tolerance and safety of a novel incremental HD regime, and to study its impact on parameters of patient wellbeing.

Method

We aim to enrol 20 patients who will commence HD twice-weekly with progressive increases in duration and frequency, achieving conventional treatment times over 15 weeks (incremental group). Participants will be followed-up for 6 months and will undergo regular tests including urine collections, bio-impedance analyses and quality-of-life questionnaires. Semi-structured interviews will be conducted to explore patients' prior expectations from HD, their motivations for

SUBMITTER: Hazara AM 

PROVIDER: S-EPMC8421284 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature