Evaluation of quantitative CMR perfusion imaging by comparison with simultaneous ¹⁵O-water-PET.

ABSTRACT:

Background

We assessed the quantitative accuracy of cardiac perfusion measurements using dynamic contrast-enhanced MRI with simultaneous ¹⁵O-water PET as reference with a fully integrated PET-MR scanner.

Methods

15 patients underwent simultaneous DCE MRI and ¹⁵O-water PET scans at rest and adenosine-stress on an integrated PET-MR scanner. Correlation and agreement between MRI- and PET-based global and regional MBF values were assessed using correlation and Bland-Altman analysis.

Results

Three subjects were excluded due to technical problems. Global mean (± SD) MBF values at rest and stress were 0.97 ± 0.27 and 3.19 ± 0.70 mL/g/min for MRI and 1.02 ± 0.28 and 3.13 ± 1.16 mL/g/min for PET (P = 0.66 and P = 0.81). The correlations between global and

SUBMITTER: Kero T 

PROVIDER: S-EPMC8421320 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature