Prognostic nomogram for predicting 5-year overall survival in Chinese patients with high-grade osteosarcoma.

ABSTRACT: This study aimed to construct a widely accepted prognostic nomogram in Chinese high-grade osteosarcoma (HOS) patients aged ≤ 30 years to provide insight into predicting 5-year overall survival (OS). Data from 503 consecutive HOS patients at our centre between 12/2012 and 05/2019 were retrospectively collected. Eighty-four clinical features and routine laboratory haematological and biochemical testing indicators of each patient at the time of diagnosis were collected. A prognostic nomogram model for predicting OS was constructed based on the Cox proportional hazards model. The performance was assessed by the concordance index (C-index), receiver operating characteristic curve and calibration curve. The utility was evaluated by decision curve analysis. The 5-year OS was 52.1% and 2.6% for th

SUBMITTER: Yao Z 

PROVIDER: S-EPMC8421452 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature