Cell-Penetrating Peptides Predicted From CASC3, AKIP1, and AHRR Proteins.

ABSTRACT: Peptides can be used as research tools and for diagnostic or therapeutic applications. Peptides, alongside small molecules and antibodies, are used and are gaining further interest as protein-protein interaction (PPI) modulators. Peptides have high target specificity and high affinity, but, unlike small molecule modulators, they are not able to cross the cell membranes to reach their intracellular targets. To overcome this limitation, the special property of the cell-penetrating peptides (CPPs) could benefit their cause. CPPs are a class of peptides that can enter the cells and with them also deliver the attached cargoes. Today, with the advancement of in silico prediction tools and the availability of protein databases, designing new and multifunctional peptides that are able to reach int

SUBMITTER: Porosk L 

PROVIDER: S-EPMC8421526 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature