First seroepidemiological investigation of human enterovirus 71 in Iran.

ABSTRACT:

Background and objectives

Human Enterovirus 71 (EV-A71) is the causative agent for many dermal to neurological diseases especially polio-like paralysis outbreaks around the world. This study, the first of this kind in Iran, aimed to find neutralizing antibodies against EV-A71 in serum of healthy individuals in different age groups based on neutralization test (NT).

Materials and methods

In this cross-sectional study, 547 serum samples were collected from healthy individuals who were referring for routine checkup tests (aged from under 6 months to over 31 years old) to Imam-Khomeini Hospital in Tehran during January-December 2015. Serum samples were examined by NT in cell culture to detect neutralizing antibodies against EV-A71. In the next step, some of the positive samples

SUBMITTER: Javadi M 

PROVIDER: S-EPMC8421584 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature