Role of the halo sign in the assessment of giant cell arteritis: a systematic review and meta-analysis.

ABSTRACT:

Objectives

This systematic review and meta-analysis aimed to evaluate the diagnostic value of the halo sign in the assessment of GCA.

Methods

A systematic literature review was performed using MEDLINE, EMBASE and Cochrane central register databases up to August 2020. Studies informing on the sensitivity and specificity of the US halo sign for GCA (index test) were selected. Studies with a minimum of five participants were included. Study articles using clinical criteria, imaging such as PET-CT and/or temporal artery biopsy (TAB) as the reference standards were selected. Meta-analysis was conducted with a bivariate model.

Results

The initial search yielded 4023 studies. Twenty-three studies (patients n = 2711) met the inclusion criteria. Prospective (11 studies)

SUBMITTER: Sebastian A 

PROVIDER: S-EPMC8421813 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature