Suicidality in individuals with Prader-Willi syndrome: a review of registry survey data.

ABSTRACT:

Introduction

Prader-Willi syndrome (PWS) is a rare, genetic, neurodevelopmental syndrome associated with hyperphagia and early onset obesity, growth and sex hormone insufficiencies, mild-to-moderate intellectual disability, and behavioral challenges such as compulsivity, anxiety, skin picking, social skills deficits and temper outbursts. Given high rates of psychiatric comorbidity and potential risk factors for suicide in PWS, this study sought a first estimate of the prevalence of suicidal ideation (SI) and attempts (SA) in the PWS population and any characteristics associated with suicidality in this population.

Methods

Using the Global Prader-Willi Syndrome Registry, we included all participants who had answered a question about SI. We examined the most recent data from t

SUBMITTER: Peleggi A 

PROVIDER: S-EPMC8422732 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature