The potential value of plasma receptor interacting protein 3 in neonates with culture-positive late-onset sepsis.

ABSTRACT:

Background

Late-onset sepsis (LOS) is a systemic inflammatory response syndrome in neonates, and the molecular mechanism of LOS is incompletely characterized. The purpose of this study was to explore the potential value of receptor interacting protein 3 (RIP3) in LOS.

Methods

63 neonates with LOS supported by positive culture and 79 neonates without sepsis were enrolled in this study from September 2019 to March 2021. Plasma RIP3 was detected by enzyme-linked immunosorbent assay (ELISA) and assessed along with the whole blood hypersensitive C-reactive protein (hs-CRP) level and platelet count (PLT). Differences in RIP3, hs-CRP and PLT between the two groups were compared. Changes in the three indicators in sepsis were also observed after treatment. The diagnostic value of in

SUBMITTER: Gao C 

PROVIDER: S-EPMC8422743 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature