Large-scale genomic analysis of antimicrobial resistance in the zoonotic pathogen Streptococcus suis.

ABSTRACT:

Background

Antimicrobial resistance (AMR) is among the gravest threats to human health and food security worldwide. The use of antimicrobials in livestock production can lead to emergence of AMR, which can have direct effects on humans through spread of zoonotic disease. Pigs pose a particular risk as they are a source of zoonotic diseases and receive more antimicrobials than most other livestock. Here we use a large-scale genomic approach to characterise AMR in Streptococcus suis, a commensal found in most pigs, but which can also cause serious disease in both pigs and humans.

Results

We obtained replicated measures of Minimum Inhibitory Concentration (MIC) for 16 antibiotics, across a panel of 678 isolates, from the major pig-producing regions of the world. For several dru

SUBMITTER: Hadjirin NF 

PROVIDER: S-EPMC8422772 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature