Megacystis in the first trimester of pregnancy: Prognostic factors and perinatal outcomes.

ABSTRACT:

Objective

To determine whether bladder size is associated with an unfavorable neonatal outcome, in the case of first-trimester megacystis.

Materials and methods

This was a retrospective observational study between 2009 and 2019 in two prenatal diagnosis centers. The inclusion criterion was an enlarged bladder (> 7 mm) diagnosed at the first ultrasound exam between 11 and 13+6 weeks of gestation. The main study endpoint was neonatal outcome based on bladder size. An adverse outcome was defined by the completion of a medical termination of pregnancy, the occurrence of in utero fetal death, or a neonatal death. Neonatal survival was considered as a favorable outcome and was defined by a live birth, with or without normal renal function, and with a normal karyotype.

Results</

SUBMITTER: Lesieur E 

PROVIDER: S-EPMC8423287 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature