Organized primary human papillomavirus-based cervical screening: A randomized healthcare policy trial.

ABSTRACT:

Background

Clinical trials in the research setting have demonstrated that primary human papillomavirus (HPV)-based screening results in greater protection against cervical cancer compared with cytology, but evidence from real-life implementation was missing. To evaluate the effectiveness of HPV-based cervical screening within a real-life screening program, the organized, population-based cervical screening program in the capital region of Sweden offered either HPV- or cytology-based screening in a randomized manner through a randomized healthcare policy (RHP).

Methods and findings

A total of 395,725 women aged 30 to 64 years that were invited for their routine cervical screening visit were randomized without blinding to either cytology-based screening with HPV triage (n = 18

SUBMITTER: Elfstrom KM 

PROVIDER: S-EPMC8423359 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature