Head-Down-Tilt Bed Rest With Elevated CO₂: Effects of a Pilot Spaceflight Analog on Neural Function and Performance During a Cognitive-Motor Dual Task.

ABSTRACT: Spaceflight has widespread effects on human performance, including on the ability to dual task. Here, we examine how a spaceflight analog comprising 30 days of head-down-tilt bed rest (HDBR) combined with 0.5% ambient CO₂ (HDBR + CO₂) influences performance and functional activity of the brain during single and dual tasking of a cognitive and a motor task. The addition of CO₂ to HDBR is thought to better mimic the conditions aboard the International Space Station. Participants completed three tasks: (1) COUNT: counting the number of times an oddball stimulus was presented among distractors; (2) TAP: tapping one of two buttons in response to a visual cue; and (3) DUAL: performing both tasks concurrently. Eleven participants (six males) underwent functional M

SUBMITTER: Mahadevan AD 

PROVIDER: S-EPMC8424013 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature