Using Latent Class Analysis to Identify Different Risk Patterns for Patients With Masked Hypertension.

ABSTRACT: Background: There is controversy whether masked hypertension (MHT) requires additional intervention. The aim of this study is to evaluate whether MHT accompanied with high-risk metabolic syndrome (MetS), as the subphenotype, will have a different prognosis from low-risk MetS. Methods: We applied latent class analysis to identify subphenotypes of MHT, using the clinical and biological information collected from High-risk Cardiovascular Factor Screening and Chronic Disease Management Programme. We modeled the data, examined the relationship between subphenotypes and clinical outcomes, and further explored the impact of antihypertensive medication. Results: We included a total of 140 patients with MHT for analysis. The latent class model showed that the two-class (high/lo

SUBMITTER: Fu M 

PROVIDER: S-EPMC8424076 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature