Circle of Willis anomalies in Turner syndrome: Absent A1 segment of the anterior cerebral artery.

ABSTRACT:

Purpose

Turner syndrome (TS) is the most common sex chromosome disorder in women and is associated with a higher than expected death rate secondary to cerebrovascular disease, including stroke. This study evaluates the cerebral vascular anatomy of individuals with TS.

Methods

Twenty-one women with TS had brain magnetic resonance angiography (MRA). These MRAs were evaluated in a blinded manner with a control group of 25 men and 25 women who had MRA imaging for multiple indications including migraine headaches, psychiatric disorders, and seizures.

Results

Twenty-nine percent of women with TS were missing an A1 segment of the anterior cerebral artery (ACA) compared to 0% in the control group (p < .001). There were no other significant differences in the circle of Willis

SUBMITTER: Kruszka P 

PROVIDER: S-EPMC8424465 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature