Effect of anti-diabetic drugs in dialysis patients with diabetes: a nationwide retrospective cohort study.

ABSTRACT:

Background

Type 2 diabetes mellitus is common in patients undergoing dialysis. However, the association between anti-diabetic drug use and survival outcomes is rarely discussed. We aimed to investigate whether continued anti-diabetic medication use affects the survival of diabetic dialysis patients and whether different hypoglycemic drug use influences prognosis.

Methods

Using a nationwide database, we enrolled patients with incident end-stage renal disease under maintenance dialysis during 2011-2015 into the pre-existing diabetes dialysis (PDD), incident diabetes after dialysis (IDD), and non-diabetic dialysis (NDD) groups. The PDD group was further subclassified into patients who continued (PDD-M) and discontinued (PDD-NM) anti-diabetic drug use after dialysis.

Results<

SUBMITTER: Ou SH 

PROVIDER: S-EPMC8424811 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature