Efficacy of tripterygium glycosides for diabetic nephropathy: a meta-analysis of randomized controlled trials.

ABSTRACT:

Backgrounds

Diabetic nephropathy (DN) is one of the most important clinical complications of diabetes mellitus (DM) and is the most common cause of end-stage renal disease. Currently, there is no highly effective medicine that can prevent, halt, or reverse the progressive course of DN. Initial clinical data showed that Tripterygium glycosides (TGs), a traditional Chinese medicine, can decrease proteinuria in patients with DN.

Objectives

The objective of the present study is to investigate the efficacy and safety of TGs for the treatment of DN through meta-analysis of randomized controlled trials (RCTs).

Methods

All RCTs of TGs for DN were collected from The China National Knowledge Infrastructure (CNKI), PubMed, Web of Science, Wanfang Data, Chinese Biomedical Literat

SUBMITTER: Guo HB 

PROVIDER: S-EPMC8425142 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature