Association between Vitamin D Status and Risk of Developing Severe COVID-19 Infection: A Meta-Analysis of Observational Studies.

ABSTRACT:

Objective

The relationship between 25-hydroxyvitamin D3 (25(OH)D), the surrogate marker for vitamin D₃, serum concentration and COVID-19 has come to the forefront as a potential pathway to improve COVID-19 outcomes. The current evidence remains unclear on the impact of vitamin D status on the severity and outcomes of COVID-19 infection. To explore possible association between low 25(OH)D levels and risk of developing severe COVID-19 (i.e. need for invasive mechanical ventilation, the length of hospital stay, total deaths). We also aimed to understand the relationship between vitamin D insufficiency and elevated inflammatory and cardiac biomarkers.

Methods

We conducted a comprehensive electronic literature search for any original research study published up to Marc

SUBMITTER: Ben-Eltriki M 

PROVIDER: S-EPMC8425440 | biostudies-literature | 2022 Sep-Oct

REPOSITORIES: biostudies-literature