I feel good? Anhedonia might not mean "without pleasure" for people treated for opioid use disorder.

ABSTRACT: Anhedonia is usually defined as partial or total loss of the capacity for pleasure. People with anhedonia in the context of major depressive disorder may have an unexpected capacity for event-related mood brightening, observable when mood is assessed dynamically (with smartphone-based ecological momentary assessment [EMA]) rather than only statically via questionnaire. We used EMA to monitor mood and pleasant events for 4 weeks in 54 people being treated with opioid agonist medication for opioid-use disorder (OUD), which is also associated with anhedonia, said to manifest especially as loss of pleasure from nondrug reward. We compared OUD patients' EMA reports with those of 47 demographically similar controls. Background positive mood was lower in OUD patients than in controls, as w

SUBMITTER: Stull SW 

PROVIDER: S-EPMC8425598 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature