Effects of Age on Esophageal Motility: A High-Resolution Manometry Study.

ABSTRACT:

Background

Studies have found possible physiologic changes to esophageal motility with aging currently not taken into account in routine high-resolution manometry (HRM) interpretation. We aimed to quantify the relationship between these physiologic changes and aging to improve HRM interpretation.

Methods

We conducted a retrospective analysis of patients who underwent HRM at a tertiary hospital center between 2015 and 2019. Inclusion criteria were patients aged ≥18 years with normal HRM. Exclusion criteria were abnormal HRM, abnormal upper digestive endoscopy or imagery. Outcomes were median integrated relaxation pressure (IRP), lower esophageal sphincter (LES) pressure, distal contractal integral (DCI), distal latency (DL), and peristaltic break (PB) according to the v4.0 Ch

SUBMITTER: Djinbachian R 

PROVIDER: S-EPMC8425793 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature