Pulmonary Function Testing Pre-heart Transplant Predicts Posttransplant Survival.

ABSTRACT: Although pulmonary function testing (PFT) is typically performed for heart transplant evaluation, the prognostic utility of PFTs after transplantation is unknown. We evaluated whether PFT parameters were correlated with outcomes following heart transplantation.

Methods

International Society for Heart and Lung Transplantation Thoracic Organ Transplant Registry data were utilized. Survival was assessed using Kaplan-Meier method and compared via log-rank test. Cox proportional hazard modeling was used to evaluate univariate and multivariate predictors of survival.

Results

Eight hundred two patients pretransplant PFT data were available for evaluation. Forced expiratory volume in 1 s (FEV1) < 50% predicted (P < 0.0001), and forced vital capacity (FVC) < 50% predicted each

SUBMITTER: Lundgren SW 

PROVIDER: S-EPMC8425848 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature