Comparison of the dosimetric accuracy of proton breast treatment plans delivered with SGRT and CBCT setups.

ABSTRACT:

Purpose

To compare the dosimetric accuracy of surface-guided radiation therapy (SGRT) and cone-beam computed tomography (CBCT) setups in proton breast treatment plans.

Methods

Data from 30 patients were retrospectively analyzed in this IRB-approved study. Patients were prescribed 4256-5040 cGy in 16-28 fractions. CBCT and AlignRT (SGRT; Vision RT Ltd.) were used for treatment setup during the first three fractions, then daily AlignRT and weekly CBCT thereafter. Each patient underwent a quality assurance CT (QA-CT) scan midway through the treatment course to assess anatomical and dosimetric changes. To emulate the SGRT and CBCT setups during treatment, the planning CT and QA-CT images were registered in two ways: (1) by registering the volume within the CTs covered by the CBC

SUBMITTER: MacFarlane MJ 

PROVIDER: S-EPMC8425866 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature